Figure 7. Expression of genes associated with cell survival in CD8⁺HLA-DR-naive, CD8⁺HLA-DR⁻ memory and CD8⁺HLA-DR⁺ cells.

(A) Expression levels of Bcl-2 and Survivin in FACS-sorted CD8⁺HLA-DR⁻ naive, CD8⁺HLA-DR-memory and CD8⁺HLA-DR⁺ cells. Mean + SEM values were calculated using cells from control (n=11), HIV+ <50 (n=9), and HIV+ ≥50 (n=7) individuals. The level of statistical significance was determined by the Mann-Whitey test. *P<0.001. (B) Levels of Bcl-2 and Survivin proteins as determined by western blot. Actin was used as a loading control. Results are representative of 3 independent experiments.