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TLM-induced inhibition of cell proliferation is independent of AT1 receptor blockade. A, Dose-dependent effects of LOS or VAL on cell growth (i and ii, respectively) and BrdU incorporation (iii) in HUVEC. B, Growth curve (i) and BrdU incorporation assay (ii) in COS-7 cells treated with 100 μmol/L TML for the indicated times. n=3; *P<0.05 vs DMSO.
