Table 1.
Participant Characteristics at Baseline, by Age-Related Macular Degeneration, Incident Coronary Heart Disease Status, and Incident Stroke Status
| AMD
|
Incident CHD
|
Incident Stroke
|
|||||
|---|---|---|---|---|---|---|---|
| Absent (n = 1423) | Early (n = 268) | Late (n = 24) | No (n = 1483) | Yes (n = 303) | No (n = 2030) | Yes (n = 198) | |
| Age, y | 77.8 | 79.8a | 82.1a | 78.0 | 79.4a | 78.3 | 79.7a |
| Male, % | 34.6 | 33.6 | 37.5 | 32.0 | 45.5a | 39.3 | 34.8 |
| African-American, % | 16.9 | 9.0a | 4.2 | 16.8 | 12.9 | 14.9 | 15.2 |
| High school graduate, % | 48.7 | 51.2 | 59.1 | 49.0 | 51.6 | 48.5 | 49.5 |
| Hypertension, % | 57.2 | 55.5 | 75.0 | 55.5 | 66.6a | 57.2 | 66.8a |
| Systolic blood pressure, mmHg | 132.1 | 130.7 | 133.9 | 131.4 | 134.6a | 131.0 | 136.7a |
| Diastolic blood pressure, mmHg | 67.1 | 67.5 | 66.4 | 67.4 | 65.9a | 66.4 | 68.0 |
| Diabetes, % | 16.1 | 14.6 | 14.3 | 14.9 | 21.0a | 17.2 | 20.1 |
| Glucose, mg/dl | 97.5 | 97.7 | 97.6 | 96.4 | 102.3a | 98.4 | 98.6 |
| Body mass index, kg/m2 | 27.1 | 26.6 | 28.5 | 26.9 | 27.4 | 27.0 | 26.9 |
| Total cholesterol, mg/dl | 205.6 | 202.9 | 198.0 | 205.7 | 203.4 | 202.3 | 206.5 |
| HDL cholesterol, mg/dl | 54.7 | 56.4 | 60.3 | 55.4 | 53.7a | 53.7 | 54.0 |
| LDL cholesterol, mg/l | 129.0 | 124.2a | 115.7 | 128.1 | 128.8 | 128.6 | 127.6 |
| Total triglyceride, mg/dl | 126.2 | 109.5a | 110.6 | 120.9 | 133.8a | 125.6 | 125.2 |
| Cigarette smoking, ever, % | 5.9 | 8.2 | 11.7 | 6.3 | 5.8 | 5.6 | 8.1 |
| Alcohol use, ever, % | 1.0 | 0.9 | 0.6 | 1.0 | 0.8 | 1.1 | 1.0 |
AMD = age-related macular degeneration; CHD = coronary heart disease; HDL = high-density lipoprotein; LDL= low-density lipoprotein.
a
P<0.05; represents differences in means or proportions, adjusted for age, gender, and ethnicity (except for mean age, male, and African-American ethnicity, which were not adjusted for age, gender, and ethnicity, respectively).