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. 2013 Nov 5;8(11):e79778. doi: 10.1371/journal.pone.0079778

Figure 4. Superposition of CARMA1 CARD with their structural homologues.

Figure 4

A. CARMA1 CARD (green color) and five structural homologues are superimposed. B. Structural-based sequence alignment. Structure-based sequence alignment of CARMA1 CARD with other CARD domains. Secondary structures (helices H1 to H6) are shown above the sequences. Residues at the hydrophobic core are shown in blue. C-G. Pair-wise structural comparisons were also performed. CARMA1 CARD is green and each counterpart is blue for Apaf-1 CARD (B), red for ICEBERG (C), cyan for caspase-9 CARD (D), magenta for NALP1 CARD (E), and gray for NOD1 CARD (F).