Table 2. Comparison of the bbfA mutant with other reported biofilm reduced strains.
Mutant | Annotation | Source | Other phenotypes | Cell lines |
wzn | ABC transporter | [9] | acapsular, ↓ oxidative survival, desiccation | |
fliC | Flagellin | [4] | aflagellate | |
cpdA | c-di-GMP phosphodiesterase | [11] | aflagellate, ↑ EPS†, autoagglutination | ↓ A549 & THP1 invasion |
pkk | polyphosphate kinase | [10] | aflagellate, ↓ oxidative survival | |
rpoE | Alternative sigma factor | [13] | ↓ oxidative & osmotic survival | ↓ J774 invasion |
bspI | QS synthase 1 | [12] | no QS 1 | |
bspI3 | QS synthase 3 | [12] | no QS 3 | |
bspR | QS regulator 1 | [12] | no QS 1 | |
bbfA | TAA | This study | wt A549 & J774 invasion |
EPS = exopolysaccharide.