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. 2013 Nov 5;8(11):e79461. doi: 10.1371/journal.pone.0079461

Table 2. Comparison of the bbfA mutant with other reported biofilm reduced strains.

Mutant Annotation Source Other phenotypes Cell lines
wzn ABC transporter [9] acapsular, ↓ oxidative survival, desiccation
fliC Flagellin [4] aflagellate
cpdA c-di-GMP phosphodiesterase [11] aflagellate, ↑ EPS, autoagglutination ↓ A549 & THP1 invasion
pkk polyphosphate kinase [10] aflagellate, ↓ oxidative survival
rpoE Alternative sigma factor [13] ↓ oxidative & osmotic survival ↓ J774 invasion
bspI QS synthase 1 [12] no QS 1
bspI3 QS synthase 3 [12] no QS 3
bspR QS regulator 1 [12] no QS 1
bbfA TAA This study wt A549 & J774 invasion

EPS =  exopolysaccharide.