Table 2.
Proteins localized to the contractile vacuole of different protists
| Protein name | CVC localization (name) | Protist | Reference |
|---|---|---|---|
| Membrane Transporters/Channels/Receptors | |||
| V-H+-ATPase | bladder /spongiome | D. discoideum | (Fok et al., 1993; Heuser et al., 1993; Rooney et al., 1994) |
| bladder | C. reinhardtii | (Ruiz et al., 2001a) | |
| bladder | T. cruzi | (Ulrich et al., 2011) | |
| bladder | A. proteus | (Nishihara et al., 2008) | |
| H+-PPase | bladder (VP1) | C. reinhardtii | (Ruiz et al., 2001a) |
| T. cruzi | (Rohloff et al., 2004) | ||
| Ca2+-ATPase | bladder (PAT1) | D. discoideum | (Marchesini et al., 2002; Moniakis et al., 1999) |
| IP3 receptor | bladder/spongiome | ||
| (CRC-II-1b) | P. tetraurelia | (Ladenburger et al., 2006) | |
| Calmodulin | bladder (CaM) | D. discoideum | (Zhu and Clarke, 1992; Zhu et al., 1993) |
| bladder (CaM) | P. multimicronucleatum | (Fok et al., 2008) | |
| spongiome (CaM) | T. cruzi | (Ulrich et al., 2011) | |
| Copine A | bladder (CpnA) | D. discoideum | (Damer et al., 2007) |
| P2X receptor | bladder (P2X) | D. discoideum | (Fountain et al., 2007; Ludlow et al., 2009; Sivaramakrishnan and Fountain, 2012a, b) |
| Ammonium transporter | bladder (Amtb) | D. discoideum | (Kirsten et al., 2008) |
| Rh50 (CO2 transporter) | bladder (RH50) | D. discoideum | (Benghezal et al., 2001) |
| Polyamine transporter | bladder (POT1.1) | T. cruzi | (Hasne et al., 2010) |
| Phosphate transporter | bladder (PHO1) | T. cruzi | (Ulrich et al., 2011) |
| Aquaporin | bladder (AQP1) | T. cruzi | (Rohloff et al., 2004) |
| bladder (AQP1) | L. major | (Figarella et al., 2007) | |
| bladder (AQP) | A. proteus | (Nishihara et al., 2008) | |
| bladder (CreMIP1) | C. reinhardtii | (Komsic-Buchmann et al., 2012) | |
| Trafficking Proteins | |||
| Rab8a | bladder /spongiome | D. discoideum | (Essid et al., 2012) |
| Rab11a | bladder /spongiome | D. discoideum | (Harris et al., 2001) |
| bladder | T. cruzi | (Ulrich et al., 2011) | |
| Rab11c | bladder/spongiome | D. discoideum | (Du et al., 2008) |
| Rab14 | spongiome (RabD) | D. discoideum | (Bush et al., 1994; Harris and Cardelli, 2002) |
| Rab 32 | bladder | T. cruzi | (Ulrich et al., 2011) |
| Disgorgin | bladder /spongiome | D. discoideum | (Du et al., 2008) |
| Drainin | bladder | D. discoideum | (Becker et al., 1999) |
| LvsA | spongiome | D. discoideum | (Gerald et al., 2002) |
| Clathrin | bladder | D. discoideum | (Heuser, 2006; Stavrou and O'Halloran, 2006) |
| AP180 | bladder | D. discoideum | (Wen et al., 2009) |
| bladder | T. cruzi | (Ulrich et al., 2011) | |
| AP2 | bladder | D. discoideum | (Wen et al., 2009) |
| Epsin | bladder | D. discoideum | (Wen et al., 2009) |
| SNARE2.1 | spongiome | T. cruzi | (Ulrich et al., 2011) |
| SNARE2.2 | spongiome | T. cruzi | (Ulrich et al., 2011) |
| Vamp7B | bladder | D. discoideum | (Wen et al., 2009) |
| SNAP-25 | bladder | P. tetraurelia | (Schilde et al., 2008) |
| Sec8 | bladder | D. discoideum | (Essid et al., 2012) |
| Sec15 | bladder | D. discoideum | (Essid et al., 2012) |
| MEGAPs | spongiome | D. discoideum | (Heath and Insall, 2008a, b) |
| Myosin 1c | bladder | D. discoideum | (Zhu and Clarke, 1992) |
| Myosin V | bladder/spongiome | (MyoJ) D. discoideum | (Jung et al., 2009) |
| Golvesin | bladder /spongiome | D. discoideum | (Gerisch et al., 2004; Schneider et al., 2000) |
| Dajumin | bladder | D. discoideum | (Gabriel et al., 1999) |
| Phosphoprotein | spongiome | C. luciliae thermophila | (Baqui et al., 2000) |
| Soluble proteins and enzymes | |||
| Alkaline phosphatase | lumen | D. discoideum | (Zhu and Clarke, 1992) |
| DdCAD-1 | lumen | D. discoideum | (Sesaki et al., 1997; Siu et al., 2011; Sriskanthadevan et al., 2009; Sriskanthadevan et al., 2011) |
| Discoidin 1 | lumen | D. discoideum | |
| Carbonic anhydrase | lumen | D. discoideum | (Ruiz et al., 2001a) |
| Phosphodiesterase C | spongiome | T. cruzi | (Schoijet et al., 2011) |
| Protein kinase | lumen | D. discoideum | (Betapudi and Egelhoff, 2009; Betapudi et al., 2005) |
| Metacaspase | bladder | D. discoideum | (Saheb et al., 2012) |