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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2013 Aug 27;22(11):10.1158/1055-9965.EPI-13-0397. doi: 10.1158/1055-9965.EPI-13-0397

Table 2.

Characteristics of hepatocellular carcinoma cases by HBV1 and HCV2 liver tissue status (n=61)

Characteristics HBV+ (n=20)
No. (%)
HBV- (n=41)
No. (%)
p value HCV+ (n=7)
No. (%)
HCV- (n=54)
No. (%)
p value
Sex
 Male 15 (75) 28 (68) 0.59 5 (71) 38 (70) 0.95
 Female 5 (25) 13 (32) 2 (29) 16 (30)
Age
 <60 13 (65) 23 (56) 0.51 3 (43) 33 (61) 0.36
 ≥60 7 (35) 18 (44) 4 (57) 21 (39)
Race3
 White 0 --- 10 (24) 0.04 1 (14) 9 (17) 0.16
 Asian/Pacific Islander 20 (100) 31 (76) 6 (86) 45 (83)
Birthplace4
 U.S. 15 (79) 11 (33) 0.002 3 (50) 23 (50) 1.00
 Asia and Pacific Island 4 (21) 22 (67) 3 (50) 23 (50)
Diagnosis year
 1990–1999 7 (35) 15 (37) 0.90 0 -- 22 (41) 0.03
 2000–2010 13 (65) 26 (63) 7 (100) 32 (59)
Stage
 Localized 14 (70) 29 (71) 0.87 4 (57) 39 (72) 0.21
 Regional/Distant 5 (25) 11 (27) 2 (29) 14 (26)
 Unstaged/Unknown 1 (5) 1 (2) 1 (14) 1 (2)
Cirrhosis5
 No 6 (35) 16 (43) 0.58 2 (29) 20 (43) 0.48
 Yes 11 (65) 21 (57) 5 (71) 27 (57)
First course of treatment
 Surgery6 17 (85) 31 (76) 0.40 6 (86) 42 (78) 0.63
 Other/none 3 (15) 10 (24) 1 (14) 12 (22)
1

Based on the detection of HBV (HBV DNA, HBsAg, and/or HBcAg) in tumor and/or non-tumor liver tissue

2

Based on the detection of HCV RNA in tumor and/or non-tumor liver tissue

3

Excludes race other than white, Asian, and Pacific Islander

4

Excludes birthplace other than U.S., Asia, and Pacific Islands; U.S. includes U.S. mainland and Hawaii only

5

Excludes 7 cases with no information on cirrhosis

6

Surgical resection or transplantation