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. 2013 Nov 5;8(11):e78028. doi: 10.1371/journal.pone.0078028

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© 2013 Han, Zheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Part A shows the proportion of disease miRNAs in all the miRNAs. Part B shows the comparisons of SNP densities in disease miRNAs and no-disease miRNAs with two sample one tailed test. In part B, *, ** and *** means -values smaller than 0.05, 0.01 and 0.001, respectively. Error bar indicate the SEM. Part C shows the distribution of the numbers of associated diseases for miRNAs in HMDD. Part D shows the number of SNPs and the number of associated diseases of the miRNAs. MiRNAs are grouped into different groups according to the number of SNPs in them and the average numbers of associated disease for all groups were calculated, shown as green triangles. The green triangles are connected with yellow lines. Part E shows the number of SNPs in the miRNAs and the number of QTLs which the miRNAs are overlapped with. MiRNAs are grouped into different groups according to the number of SNPs in them and the average number of QTLs for each group was calculated, shown as green triangles. The green triangles are connected with yellow line.

Inline graphic — Part A shows the proportion of disease miRNAs in all the miRNAs. Part B shows the comparisons of SNP densities in disease miRNAs and no-disease miRNAs with two sample one tailed test. In part B, *, ** and *** means -values smaller than 0.05, 0.01 and 0.001, respectively. Error bar indicate the SEM. Part C shows the distribution of the numbers of associated diseases for miRNAs in HMDD. Part D shows the number of SNPs and the number of associated diseases of the miRNAs. MiRNAs are grouped into different groups according to the number of SNPs in them and the average numbers of associated disease for all groups were calculated, shown as green triangles. The green triangles are connected with yellow lines. Part E shows the number of SNPs in the miRNAs and the number of QTLs which the miRNAs are overlapped with. MiRNAs are grouped into different groups according to the number of SNPs in them and the average number of QTLs for each group was calculated, shown as green triangles. The green triangles are connected with yellow line.