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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Biol Psychiatry. 2013 Sep 5;74(11):10.1016/j.biopsych.2013.07.032. doi: 10.1016/j.biopsych.2013.07.032

Figure 2. In the BNSTov STEP immunoreactivity co-localizes with CRF but not NPY or ENK.

Figure 2

A-A″ At higher magnification CRF-positive cells (A, closed arrows) and STEP-positive (A′, open arrows) showed almost complete co-localization in the BNSTov (A″, double arrows). However, there are occasional STEP-immunoreactive neurons which do not appear to co-localize CRF (A″, open arrows). B-B″ STEP-positive neurons (B′, green, open arrows) do not co-localize with NPY (B, red, closed arrows), or ENK (C-C″). ENK-positive processes are observed to make perisomatic contacts with STEP-expressing neurons (C″, double arrow). (NPY-Neuropeptide Y, ENK-Enkephalin, 63x, scale bar 10 μm).