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. Author manuscript; available in PMC: 2014 Dec 15.
Published in final edited form as: Psychiatry Res. 2013 Aug 22;210(2):10.1016/j.psychres.2013.07.015. doi: 10.1016/j.psychres.2013.07.015

Table 6a. Sensitivity and specificity for MDD diagnosis across various cut-off points of the PHQ-9 by sex.

Sensitivity (95%CI) Specificity (95%CI) Youden Index LR+(95%CI) LR- (95%CI) PPV (95%CI) NPV (95%CI)
All participants
 Score≥9 90.4 (82.6-95.5) 61.7 (55.6-67.5) 52.1 2.6 (2.0-2.8) 0.2 (0.1-0.3) 45.2 (38.0-52.6) 94.9 (90.5-97.6)
 Score≥10 86.2 (77.5-92.4) 67.3 (61.3-72.9) 53.5 2.6 (2.2- . 3.2) 0.2 (0.1-0.3) 47.9 (40.2-55.7) 93.3 (88.8-96.4)
 Score≥11 78.7 (69.1-86.5) 74.0 (68.3-79.1) 52.7 3.4 (3.0-3.9) 0.3 (0.2-0.5) 54.3 (45.3-63.2) 89.4 (84.8-93.0)
Women
 Score≥9 90.1 (80.7-95.9) 62.0 (54.0-69.6) 52.1 2.4 (1.9-2.9) 0.2 (0.1-0.3) 51.0 (42.5-60.7) 93.3 (86.7-97.3)
 Score≥10 85.9 (75.6-93.0) 68.4 (60.5-75.5) 54.3 2.9 (2.5-3.5) 0.2 (0.1-0.4) 55.0 (45.2-64.4) 91.5 (85.0-95.9)
 Score≥11 81.7 (70.7-89.9) 72.2 (64.5-79.0) 53.9 2.9 (2.2-3.9) 0.3 (0.1-0.4) 56.9 (46.7-66.6) 89.8 (83.1-94.4)
Men
 Score≥9 91.3 (72.0-98.9) 61.3 (51.5-70.4) 52.6 2.4 (1.8-3.1) 0.2 (0.1-0.5) 32.8 (21.6-45.7) 97.1 (90.1-99.7)
 Score≥10 87.0 (66.4-97.2) 65.8 (56.2-74.5) 52.8 2.5 (1.9-3.4) 0.2 (0.1-0.6) 34.5 (22.5-48.1) 96.1 (88.9-99.2)
 Score≥11 69.6 (47.1-86.8) 76.6 (67.6-84.1) 46.1 2.9 (1.9-4.6) 0.4 (0.2-0.7) 38.1 (23.6-54.4) 92.4 (84.9-96.9)

LR+: positive likelihood ratio, LR-: negative likelihood ratio, PPV: positive predictive value, NPV: negative predictive value