Table 6b. Sensitivity and specificity for MDD diagnosis using different PHQ-9 screening criteria.

	Sensitivity (95%CI)	Specificity (95%CI)	LR+(95%CI)	LR-(95%CI)	PPV(95%CI)	NPV (95%CI)
PHQ-9 score ≥9, at least one cardinal symptom scored ≥2	78.3 (63.6-89.1)	64.0 (58.5-69.3)	2.1 (1.8-2.7)	0.3 (0.2-0.6)	24.0 (17.4-31.6)	95.3 (91.5-97.7)
At least 5 symptoms scored ≥ 2, at least 1 cardinal symptom	50.0 (34.9-65.1)	84.2 (79.7-88.1)	3.2 (2.2-4.7)	0.6 (0.4-0.8)	31.5 (21.1-43.4)	92.1 (88.3-94.9)
At least 5 symptoms scored ≥ 1, at least 1 cardinal symptom	89.1 (76.4-96.4)	42.9 (37.4-48.6)	1.6 (1.4-1.8)	0.2 (0.1-0.6)	18.5 (13.6-24.2)	96.5 (91.9-98.8)
At least one cardinal symptom scored ≥ 2	78.3 (63.6-89.1)	54.9 (49.2-60.5)	*1.7 (1.4-2.1)	0.4 (0.2-0.6)	20.1 (14.5-26.7)	94.6 (90.2-97.4)

LR+: positive likelihood ratio, LR-: negative likelihood ratio, PPV: positive predictive value, NPV: negative predictive value