Table 2.
Six-Month Smoking Outcomes by Intervention Arm.
| INTERVENTION GROUP |
|||||
|---|---|---|---|---|---|
| Full Cohort (n = 315) | NRT (n = 133) | Varenicline (n = 137) | Placebo (n = 45) | ||
|
|
|||||
| Outcome | Mean (± SD) or n (%) | Mean (± SD) or n (%) | Mean (± SD) or n (%) | Mean (± SD) or n (%) | Wald χ2 (p = ) b |
| Self-Reported 7-Day Abstinence | |||||
| Yes | 30 (9.5%) | 16 (12.0%) | 11 (8.0%) | 3 (6.7%) | 1.72 (.423) |
| No | 285 (90.5%) | 117 (88.0%) | 126 (92.0%) | 42 (93.3%) | |
| CO-Confirmed 7-Day Abstinence a | |||||
| Yes | 17 (5.4%) | 11 (8.3%) | 5 (3.7%) | 1 (2.2%) | 3.56 (.168) |
| No | 298 (94.6%) | 122 (91.7%) | 132 (96.4%) | 44 (97.8%) | |
| Change Mean Cigarettes / Day | −8.3 (± 9.3) | −7.8 (± 9.4) | −8.7 (± 9.2) | −8.5 (± 9.5) | 0.76 (.684) |
| Continuous Abstinence | |||||
| Yes | 4 (1.3%) | 2 (1.5%) | 2 (1.5%) | 0 (0.0%) | 0.00 (.999) |
| No | 311 (98.7%) | 131 (98.5%) | 135 (98.5%) | 45 (100.0%) | |
a
Valid CO or Cotinine tests were available for 199 participants. Participants without valid CO tests were assumed non-abstinent. Separate analysis of participants with valid CO or Cotinine tests was consistent with the results reported here (χ2 = 3.12, p = .190).
b
Mixed logistic and linear regression models with data collection site entered as a random effect were estimated to test the statistical significance of intervention. The intraclass correlations representing the effect of site were trivially small; analyses treating observations as independent gave results substantively and statistically consistent with those reported here.