Table 1. Behavior of sensory and pheromone mutants.
Genotype | Gene function | Sensory defect | Directionality | p-value |
che-2 | cilia formation | chemotaxis (‘ctx’) | defective | 0.003 (vs. WT) |
daf-19* | cilia formation (master regulator) | chemotaxis (‘ctx’) | partially defective | 0.03 (vs. WT) |
osm-9 | sensory transduction (TRPV-related channel) | avoidance of repulsive compounds; nociception; ctx to some volatile compounds | wild-type | 0.0008 (vs. CRW) |
tax-4(p678) | sensory transduction (cGMP-gated channel) | thermotaxis; aerotaxis; ctx to some volatile and soluble compounds. | defective | 0.008 (vs. WT) |
tax-4(ks28) | sensory transduction (cGMP-gated channel) | same as tax-4(p678) | defective | 0.006 (vs. WT) |
tax-2 | sensory transduction (cGMP-gated channel) | same as tax-4(p678) | defective | 0.009 (vs. WT) |
gcy-8;gcy-18;gcy-23 | sensory transduction (guanylyl cyclases) | thermotaxis | wild-type | 0.0003 (vs. CRW) |
gcy-31;gcy-33;gcy-35 | sensory transduction (guanylyl cyclases) | aerotaxis | wild-type | 0.003 (vs. CRW) |
gcy-36::EGL-1 | sensory neurons ablated | aerotaxis | wild-type | 0.0002 (vs. CRW) |
odr-1 | sensory transduction (guanylyl cyclase) | ctx to volatile compounds sensed by TAX-4 neurons; phototactic avoidance | wild-type | 0.004 (vs. CRW) |
che-1 | sensory transduction (specification of sensory neuronal fate) | ctx to soluble compounds | wild-type | 0.02 (vs. CRW) |
daf-22 | C. elegans pheromone synthesis | dauer formation | wild-type | 0.01 (vs. CRW) |
Significance is estimated with respect to the wild-type scanner-array data-set (‘WT’) or to the correlated random walk model (‘CRW’). *daf-19 mutants were assayed in a daf-16 background to bypass constitutive dauer formation.