Table 2.

Tests and questionnaires for the TTM main trial and cognitive sub-study

Instrument	Abbreviation	TTM Main trial	Sub study	Area	Test administration
					PS	PO	IS	ER
Short Form Questionniare-36 version 2	SF-36v2©	■	■	Health related quality of life	■		■
Two Simple Questions	TSQ	■		Everyday activities/cognition	■
Informant Questionnaire on Cognitive Decline	IQCODE	■		Cognition			■
MiniMental Status Examination	MMSE	■		Cognition		■
Cerebral Performance Category	CPC	■		General neurological outcome				■
modified Rankin Scale	mRS	■		General outcome				■
Rivermead Behavioural Memory Test	RBMT		■	Memory		■
Symbol Digit Modalities Test	SDMT		■	Attention/Concentration/Mental speed		■
Frontal Assessment Battery	FAB		■	Executive functions		■
Hospital Anxiety and Depression Scale	HADS©		■	Anxiety/Depression	■
Mayo-Portland Adaptability Inventory-4	MPAI-4		■	Impairments/Adjustment/Participation	■
Zarit Burden Interview	ZBI©		■	Caregiver burden			■

PS= Patient Subjective PO= Patient Objective IS= Informant Subjective ER= Examiner rating.