Table 6. Diagnostic performance values in the derivation and validation group for the recognition of diastolic dysfunction.
| Parameter (cut-off value) | AUC | Sensitivity | Specificity | PPV | NPV | Accuracy |
|---|---|---|---|---|---|---|
| Age (≥58 years) | 0.86 | 83% | 75% | 76% | 82% | 77% |
| PQ (≥150 ms) | 0.65 | 78% | 46% | 58% | 68% | 62% |
| LA ESVI (≥34 ml/m2) | 0.85 | 39% | 100% | 100% | 56% | 66% |
| Septal e’ (≤8 cm/s) | 0.87 | 93% | 56% | 76% | 83% | 78% |
| Lateral e’ (≤10 cm/s) | 0.84 | 85% | 70% | 80% | 76% | 79% |
| Septal E/e’ ratio (≥8) | 0.79 | 83% | 48% | 71% | 65% | 69% |
| Septal E/e’ ratio (≥15) | 0.79 | 34% | 96% | 93% | 49% | 59% |
| Tend - P (≤311 ms) | 0.82 | 79% | 72% | 74% | 78% | 76% |
| Tend - Q (≤455 ms) | 0.77 | 72% | 73% | 73% | 73% | 73% |
| Tend - P / (PQ x Age) (≥0.0333) | 0.96 | 90% | 92% | 91% | 90% | 91% |
| Tend - Q / (PQ x Age) (≥0.0489) | 0.95 | 89% | 94% | 94% | 90% | 91% |
| LAESVI & Tend - P / (PQ x Age) | 0.98 | 96% | 100% | 100% | 97% | 98% |
| Sep E/e’ & Tend - P / (PQ x Age) | 0.96 | 95% | 100% | 100% | 95% | 98% |
| Validation Group | ||||||
| Tend - P / (PQ x Age) (≥0.0333) | 0.91 | 82% | 93% | 93% | 82% | 88% |
| LAESVI & Tend - P / (PQ x Age) | 0.95 | 90% | 92% | 95% | 86% | 91% |
| Sep E/e’ & Tend - P / (PQ x Age) | 0.83 | 95% | 57% | 76% | 89% | 79% |
AUC indicates the area under curve as assessed by ROC-Analysis, PPV positive predictive value, NPV negative predictive value