Table 2. Pooled measures for the association between the PAI-1 -675 4G/5G polymorphism and susceptibility to diabetes.
Comparisions | Data | n | Heterogeneity | OR (95% CI) | Model | p | |||
---|---|---|---|---|---|---|---|---|---|
Studies | Cases | Controls | I 2 (%) | P | |||||
Allelic comparisions | Overall | 6 | 1333 | 3011 | 0 | 0.845 | 1.07 (0.96-1.20) | REM | 0.234 |
Asian | 3 | 658 | 334 | 0 | 0.484 | 1.07(0.88-1.30) | REM | 0.502 | |
European | 3 | 665 | 2677 | 0 | 0.696 | 1.06(0.90-1.18) | REM | 0.324 | |
Dominant | Overall | 6 | 1333 | 3011 | 0 | 0.835 | 1.16(0.96-1.40) | REM | 0.123 |
Recessive | Overall | 6 | 1333 | 3011 | 0 | 0.447 | 1.04(0.88-1.24) | REM | 0.655 |
Co-dominant | Overall | 6 | 654 | 1508 | 0 | 0.896 | 1.18(0.94-1.47) | REM | 0.155 |
Note: Allelic comparisions, 4G vs. 5G; REM, Random effect model.