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. 2013 Nov 5;8(11):e79150. doi: 10.1371/journal.pone.0079150

Table 2. Pooled measures for the association between the PAI-1 -675 4G/5G polymorphism and susceptibility to diabetes.

Comparisions Data n Heterogeneity OR (95% CI) Model p
Studies Cases Controls I 2 (%) P
Allelic comparisions Overall 6 1333 3011 0 0.845 1.07 (0.96-1.20) REM 0.234
Asian 3 658 334 0 0.484 1.07(0.88-1.30) REM 0.502
European 3 665 2677 0 0.696 1.06(0.90-1.18) REM 0.324
Dominant Overall 6 1333 3011 0 0.835 1.16(0.96-1.40) REM 0.123
Recessive Overall 6 1333 3011 0 0.447 1.04(0.88-1.24) REM 0.655
Co-dominant Overall 6 654 1508 0 0.896 1.18(0.94-1.47) REM 0.155

Note: Allelic comparisions, 4G vs. 5G; REM, Random effect model.