Table 1.

Criteria for computational models of cell replacement.

I.	Accurate anatomical and circuit-level representations
II.	Response to injury in an experimentally-validated manner
III.	Incorporation of behavioral metric(s) that can be measured clinically in patients
IV.	Transplants should include all relevant physiological and anatomical features.
V.	Transplants should include temporal dynamics of synaptic connectivity and functional maturation.