Table 1.

Baseline characteristics

Characteristic	Total Met-Hours per Week
	< 3	3 – 17.9	≥ 18	overall
Number. of patients	81	96	60	237
Median total MET-hours per week	0.6	8.3	36	7.7
Median age (years)	63	60	59.5	61
Gender, n (%)
Male	38 (46.9)	59 (61.5)	43 (71.7)	140 (59.1)
Female	43 (53.1)	37 (38.5)	17 (28.3)	97 (40.9)
Race, n ( %)
White	70 (86.4)	91 (94.8)	55 (91.7)	216 (91.1)
Black	8 (9.9)	3 (3.1)	3 (5)	14 (5.9)
Other	3 (3.7)	2 (2.1)	2 (3.3)	7 (3.0)
Time from diagnosis to recurrence, years, n (%)
< 2 years	34 (42.0)	45 (46.9)	28 (46.7)	107 (45.1)
≥ 2 years	47 (58.0)	51 (53.1)	32 (53.3)	130 (54.9)
BMI, median	30.3	28	29.6	28.8
Depth of invasion through bowel wall, n (%)
T1–2	6 (7.4)	7 (7.3)	5 (8.3)	18 (7.6)
T3–4	72 (88.9)	88 (91.7)	54 (90)	214 (90.3)
missing	3 (3.7)	1 (1)	1 (1.7)	5 (2.1)
Number of positive lymph nodes, n (%)
1–3 (N1)	54 (66.7)	54 (56.3)	32 (53.3)	140 (59.1)
4+ (N2)	24 (29.6)	41 (42.7)	27 (45.0)	92 (38.8)
Missing	3 (3.7)	1 (1)	1 (1.7)	5 (2.1)
Baseline performance status, n (%)
0	52 (64.2)	70 (72.9)	48 (80)	170 (71.7)
1,2	26 (32.1)	25 (26.0)	11 (18.3)	62 (26.2)
Missing	3 (3.7)	1 (1)	1 (1.7)	5 (2.1)
Treatment, n (%)
5FU/LV	41 (50.6)	44 (45.8)	27 (45)	112 (47.3)
CPT-11/5FU/LV	40 (49.4)	52 (54.2)	33 (55.0)	125 (52.7)

5-FU = 5-fluorouracil; LV = leucovorin; IFL = irinotecan,; kg = kilograms; m² = meters squared; MET = metabolic equivalent tasks

^† Baseline performance status: PS 0 = fully active; PS 1 = restricted in physically strenuous activity but ambulatory and able to carry out light work; PS 2 = ambulatory and capable of all self-care but unable to carry out any work activities, up and about more than 50% of waking hours.

^‡ T1–2 = level of invasion through the bowel wall not beyond the muscle layer; T3–4 = level of invasion through the bowel wall beyond the muscle layer.