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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Basic Res Cardiol. 2013 Jul 16;108(5):10.1007/s00395-013-0370-0. doi: 10.1007/s00395-013-0370-0

Fig. 1.

Fig. 1

KV channel inhibition increases intracellular Ca2+ and coronary active tension. a Time course tracing of Fura-2 experiments in isolated coronary myocytes showing effect of 4AP on F345/F380 in response to 120 mM KCl (scale bar 30 s). b 4AP (0.3 mM) significantly increased KCl-mediated elevations in intracellular Ca2+ (P < 0.05). c Active tension development in isolated coronary artery segments in response to the CaV1.2 channel agonist BayK 8644 (10 μM) was significantly increased by 4AP (*P < 0.01)