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KV and CaV1.2 coupling in lean and obese swine. a Active tension development in response to KCl (20 mM) is elevated in arteries from obese relative to lean swine. 4AP increased this response in arteries from lean but not obese swine. b Baseline coronary resistance is increased by 4AP in lean swine while the change in response to nifedipine is markedly elevated in obese swine. *P < 0.05 vs. lean, †P < 0.05 vs. control
