Table 4.
Physical properties of liquisolid compacts.
| Formulation | Hardness (Kg/cm2) | Friability (%) | Disintegration time (min) | % Drug content |
|---|---|---|---|---|
| LSA 1 | 4.3 ± 0.3 | 0.82 ± 0.01 | 210 ± 0.40 | 95.33 ± 2.21 |
| LSA 2 | 4.4 ± 0.2 | 0.83 ± 0.02 | 190 ± 0.20 | 94.14 ± 2.74 |
| LSA 3 | 4.5 ± 0.4 | 0.80 ± 0.03 | 190 ± 0.20 | 97.58 ± 2.18 |
| LSA 4 | 4.1 ± 0.3 | 0.76 ± 0.02 | 170 ± 0.40 | 96.29 ± 2.47 |
| LSA 5 | 4.6 ± 0.4 | 0.77 ± 0.01 | 150 ± 0.20 | 97.53 ± 1.10 |
| LSA 6 | 4.5 ± 0.2 | 0.75 ± 0.02 | 140 ± 0.35 | 95.48 ± 2.25 |
| LSA 7 | 4.3 ± 0.3 | 0.72 ± 0.01 | 120 ± 0.40 | 94.24 ± 2.21 |
| LSA 8 | 4.5 ± 0.2 | 0.71 ± 0.02 | 130 ± 0.20 | 96.75 ± 2.74 |
| LSA 9 | 4.5 ± 0.4 | 0.75 ± 0.03 | 110 ± 0.20 | 96.88 ± 2.18 |
| LSA 10 | 4.7 ± 0.3 | 0.77 ± 0.02 | 120 ± 0.40 | 97.46 ± 2.47 |
| LSA 11 | 4.6 ± 0.4 | 0.81 ± 0.01 | 110 ± 0.20 | 95.37 ± 1.10 |
| LSA 12 | 4.7 ± 0.2 | 0.74 ± 0.02 | 110 ± 0.35 | 97.18 ± 2.25 |
| LSA 13 | 4.6 ± 0.3 | 0.71 ± 0.01 | 100 ± 0.40 | 94.63 ± 2.21 |
| LSA 14 | 4.8 ± 0.2 | 0.65 ± 0.02 | 110 ± 0.20 | 96.07 ± 2.74 |
| LSA 15 | 4.8 ± 0.4 | 0.68 ± 0.03 | 100 ± 0.20 | 98.86 ± 2.18 |
| LSA 16 | 4.5 ± 0.3 | 0.76 ± 0.02 | 90 ± 0.40 | 96.45 ± 2.47 |
| LSA 17 | 4.4 ± 0.4 | 0.67 ± 0.01 | 100 ± 0.20 | 97.76 ± 1.10 |
| LSA 18 | 4.6 ± 0.2 | 0.65 ± 0.02 | 90 ± 0.35 | 98.87 ± 2.25 |