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. Author manuscript; available in PMC: 2013 Nov 6.
Published in final edited form as: Intensive Care Med. 2011 Jul 8;37(10):10.1007/s00134-011-2304-3. doi: 10.1007/s00134-011-2304-3

Table 1.

Effect of tidal volume, increased ITP, and decreased contractility on PP, SV, and ITBV changes

PP (mmHg)
SV (ml)
PPV (%) SVV (%) ITBV change (ml)
min max min max
Vt (ml/kg) (n = 6)
 5 27 ± 12 31 ± 12 21 ± 7 24 ± 9 15 ± 6 14 ± 4 8.6 ± 3.1
 10 23 ± 10 29 ± 11 21 ± 6 27 ± 8 25 ± 8 25 ± 10 19.0 ± 10
 15 21 ± 9 29 ± 10 20 ± 6 29 ± 10 33 ± 13 34 ± 9 27.2 ± 6.6
 25 19 ± 9 29 ± 11 18 ± 6 28 ± 8 42 ± 12 43 ± 7 33.1 ± 7.9
Increased ITP (n = 6)
 Baseline 25 ± 9 31 ± 11 20 ± 5 26 ± 6 24 ± 6 24 ± 10 15.9 ± 5.9
 Thoraco-abdominal binding 23 ± 7 34 ± 11 19 ± 6 28 ± 8 39 ± 6 40 ± 4 22.2 ± 9.0
Decreased cardiac contractility (n = 4)
 Baseline 26 ± 7 37 ± 5 19 ± 6 26 ± 7 37 ± 24 32 ± 16 16.3 ± 6.2
 AVF 22 ± 6 28 ± 6 15 ± 6 21 ± 9 26 ± 13 27 ± 11 9.7 ± 5.6

PP, SV, PPV, and SVV values obtained during a three-breath period

Vt tidal volume, PP pulse pressure, SV stroke volume, PPV pulse pressure variation, SVV stroke volume variation, ITBV change intrathoracic blood volume change (average blood volume swing over a three-breath period), ITP intrathoracic pressure, AVF acute ventricular failure