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Effect of application surface area on oxybutynin bioavailability (n = 21)
| Parameter, mean (SD) | 400 cm2 area | 800 cm2 area |
|---|---|---|
| AUC [0–72 h], ng h/mL | 126.91 (83.69) | 143.04 (81.30) |
| Cmax, ng/mL | 3.70 (2.95) | 3.80 (2.32) |
| Tmax, h | 48.57 (14.33) | 43.81 (15.82) |
Abbreviations: AUC, area under the plasma concentration–time curve; Cmax, maximum measured plasma concentration; SD, standard deviation; Tmax, time to maximum measured plasma concentration.
