Table 3.
Perioperative characteristics of patients with and without intraoperative hypotension. Intraoperative hypotension is defined as maternal systolic blood pressure below 80% of baseline and an absolute value less than 90 mmHg. Only nifedipine exposure patients were included to minimize confounder. The Cincinnati staging system, which integrates the severity of cardiomyopathy into IIIa (mild cardiomyopathy), IIIb (moderate cardiomyopathy), IIIc (severe cardiomyopathy), and IV (hydrops), was used to compare the severity of TTTS in this study.
| Hypotension (n = 113) | No hypotension (n = 93) | P value | |
|---|---|---|---|
| Preoperative | |||
| Gestational age at procedure (week) | 21.4 ± 2.4 | 20.9 ± 2.6 | 0.148 |
| Cincinnati staging | |||
| (i) IIIa | 14 (12.4%) | 9 (9.7%) | 0.653 |
| (ii) IIIb | 23 (20.4%) | 19 (20.4%) | |
| (iii) IIIc | 67 (59.3%) | 58 (62.4%) | |
| (iv) IV | 9 (8.0%) | 7 (7.5%) | |
| Intraoperative | |||
| Surgery time (min) | 64.8 ± 24.3 | 63.0 ± 23.0 | 0.590 |
| Anesthesia time (min) | 100.6 ± 26.3 | 96.0 ± 24.6 | 0.206 |
| Duration of intraoperative hypotension (min) | 25.6 ± 22.9 | 0 | |
| Number of patients who received intraoperative vasopressor | 113 (100%) | 88 (94.6%) | 0.013 |
| Number of vasopressor treatments | 8.24 ± 4.82 | 3.42 ± 2.37 | <0.001 |
| Postoperative | |||
| Donor twin | |||
| Gestational age at birth (week) | 30.5 ± 4.1 | 30.7 ± 3.4 | 0.713 |
| Body weight at birth (g) | 1371.1 ± 626.2 | 1416.6 ± 604.4 | 0.683 |
| Recipient twin | |||
| Gestational age at birth (week) | 30.5 ± 4.1 | 30.7 ± 3.4 | 0.713 |
| Body weight at birth (g) | 1623.8 ± 626.8 | 1627.4 ± 620.4 | 0.973 |
Data shown in mean ± SD, or number (%).