Table 1.
Clinical characteristics of cohort stratified by renal histopathology
| Crescentic GN n = 18 | Focal GN n = 20 | Mixed n = 27 | Sclerotic n = 11 | p-value | |
|---|---|---|---|---|---|
| Mean age at biopsy, years (±SD) |
61 ± 13 |
56 ± 15 |
57 ± 17 |
60 ± 17 |
0.749 |
| Female (%) |
7 (38) |
6 (28) |
15 (55) |
5 (50) |
0.354 |
| African-American (%) |
1 (5) |
5 (24) |
7 (26) |
1 (10) |
0.240 |
| ANCA positive (%) |
16 (89) |
15 (75) |
22 (81) |
9 (82) |
0.749 |
| cANCA positive (%) |
12 (67) |
7 (33) |
10 (37) |
1 (10) |
0.018 |
| pANCA positive (%) |
4 (22) |
8 (40) |
12 (44) |
8 (73) |
0.064 |
| New vasculitis diagnosis at biopsy (%) |
16 (89) |
18 (90) |
20 (74) |
6 (55) |
0.076 |
| Clinical vasculitis phenotype |
|
|
|
|
|
| Granulomatosis with polyangiitis (%) |
15 (83) |
8 (38) |
18 (67) |
2 (20) |
0.002 |
| Microscopic polyangiitis (%) |
3 (16) |
11 (55) |
8 (30) |
9 (82) |
0.002 |
| Renal limited vasculitis (%) | 0 (0) | 1 (5) | 1 (4) | 0 (0) | 0.719 |