Table 6.

Correlations of MMPs with HIV clinical variables

	Plasma (n=48)					CSF (n=9)
Clinical Variables	MMP-1	MMP-2	MMP-7	MMP-9	MMP-10	MMP-2	MMP-9
CD4+ cell count	−0.154	0.052	0.107	0.234	−0.061	−0.400	−0.333
CD8+ cell count	−0.278†	−0.228	−0.171	0.083	0.048	−0.817**	−0.117
CD4/CD8 ratio	0.144	0.285*	0.218	0.096	−0.144	0.427	−0.326
HIV RNA (viral load)	0.036	−0.054	−0.298*	−0.199	0.006	0.100	0.267
Hemoglobin	0.047	−0.181	0.068	0.105	−0.101	0.433	−0.417

Pearson correlation coefficients (Spearman used for MMP-9 and CSF).

^**Significant at the 0.01 level.

^*Significant at the 0.05 level.

^†Nearly significant (p < 0.10).