Table 7.

Correlations of MMPs with cognitive status measures

	Plasma (n=69)					CSF (n=9)
Cognitive Measures	MMP-1	MMP-2	MMP-7	MMP-9	MMP-10	MMP-2	MMP-9
Verbal Memory
RAVLT	−0.283*	0.101	−0.059	−0.010	−0.039	−0.311	−0.664†
LNS	−0.286*	0.235†	−0.061	0.067	−0.011	0.238	−0.204
Visual Memory
ROCF Recall	−0.200†	0.175	−0.108	0.086	0.021	−0.610	−0.464
Visuoconstruction
ROCF Copy	−0.218†	0.240†	0.007	−0.119	0.082	−0.325	0.012
Frontal Executive
Verbal Fluency	−0.009	0.223†	−0.159	0.149	0.015	0.233	−0.683*
Odd Man Out	−0.205†	0.064	0.014	−0.125	−0.083	−0.186	−0.319
Trail-making	0.350**	−0.084	0.084	−0.142	0.254*	0.201	0.435
Psychomotor
Digit Symbol	−0.175	0.079	−0.167	0.208†	−0.110	−0.075	0.209
CALCAP Choice	0.100	−0.005	0.013	−0.184	−0.157	0.444	−0.184
CALCAP Sequential	0.072	0.061	−0.056	−0.134	−0.061	0.100	−0.276
Motor Speed
Grooved Pegboard	0.127	−0.038	0.111	0.042	0.128	−0.669*	0.351
Timed Gait	−0.138	0.091	0.359**	−0.010	0.033	−0.305	−0.322

Pearson correlation coefficients (Spearman used for MMP-9 and CSF).

RAVLT: Rey Auditory Verbal Learning Test; ROCF: Rey-Osterrieth Complex Figure; CALCAP: California Computerized Assessment Package; LNS: Letter Number Sequencing

Bold correlation coefficient: Significant at the Bonferroni corrected level of 0.05/18.

^**Significant at the 0.01 level.

^*Significant at the 0.05 level.

^†Nearly significant (p < 0.10).