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Truncation of podocalyxin exon 2 induces mild pericardial edema. (A1 and B1) Whole-body images of 2-dpf larvae. Approximately 40% of podxlMOex2 morphants have mild pericardial edema (arrow in B1). (A2 and B2) Hematoxylin–eosin-stained sections reveal that the pronephric glomerulus in the podxlMOex2 exhibits developed glomerular capillary and mesangium at 4 dpf (B2), as that seen in control (A2). Bar scales: 250 μm in A1, B1; 10 μm in A2, B2.
