Figure 5. Ligand-dependent co-localization of CXCR7 and β-arrestin 2 on endosomes.
293T cells transiently transfected with CXCR7-GFP and β-arrestin 2-mCherry were treated for 30 minutes with vehicle only, 300 ng/ml CXCL12, or 300 μM of listed peptides. Images show separate green, red, and merged images from confocal microscopy. White arrows highlight some endosomes with co-localization of CXCR7-GFP and β-arrestin 2-mCherry. Scale bar denotes 10 μm.