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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Vascul Pharmacol. 2013 Jun 6;59(0):10.1016/j.vph.2013.06.001. doi: 10.1016/j.vph.2013.06.001

Fig. 3.

Fig. 3

PR regulation of cytokine and chemokine expression.(A) Heat map depicting differential expression of cytokine and chemokines strongly regulated by LPS stimulation of HUVECs for 4 and 8 h compared to nontreated cells. (B) Heat map comparing differential gene expression between LPS treatment in the presence or absence of progesterone. Genes included those found to be significantly (p < 0.01) upregulated by LPS treatment as determined from the heat map in panel A. (C) Heat map comparing differential gene expression between HUVECs treated with or without progesterone. Genes analyzed were those that were significantly (p < 0.01) downregulated by progesterone in the heat map from panel B. + symbolizes genes that were found to be directly bound by PR by ChIP-seq analysis