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. 2013 Nov 6;8(11):e79754. doi: 10.1371/journal.pone.0079754

Table 3. Regression analysis of association between composite harm score and health outcome measuresa.

Health outcome measure n Adjusted estimates of CHS effect (95% CI)b p–value
Physical health
Mortality 288 1.47 (1.07–2.01) 0.016
Hepatitis C virus exposure 279 1.56 (1.28–1.92) <0.001
Hepatitis C virus persistent infection 185 1.29 (1.02–1.67) 0.043
Psychological health
Psychotic illness 286
None (reference) 1.00
Functional psychosis 0.73 (0.56–0.93) 0.014
Psychosis not otherwise specified 1.11 (0.89–1.38) 0.348
Substance–induced psychosis 1.39 (1.13–1.67) 0.001
Depressive illness 288 1.11 (0.93–1.32) 0.251
Substance dependence diagnoses 287 2.69 (2.29–3.19) <0.001
Social health
Role functioning scale 284 -0.02 (-0.27–0.23) 0.875
SOFAS 287 -0.44 (-1.22–0.34) 0.270
Committed a crime in past month 283 1.74 (1.46–2.10) <0.001
Drug trafficking 283 1.97 (1.61–2.45) <0.001
Theft 283 1.16 (0.93–1.44) 0.177
Any employment in past month 281 0.92 (0.73–1.13) 0.415
Drug spending in past month 283 1.51 (1.40–1.62) <0.001
Multimorbidity score (0-12) 288 1.43 (1.26-1.63) <0.001

a Binary logistic regression was used to model the relationship between CHS and mortality, hepatitis C virus exposure, persistent hepatitis C Infection, depression, employment and committing any crime, drug trafficking or theft. Ordinal logistic regression was used to model the relationship between CHS and number of multimorbid illnesses and dependence diagnoses. Multinomial logistic regression was used to model the relationship between CHS and psychotic illness diagnosis. Linear regression was used to model the relationship between CHS and Role Functioning Score, and SOFAS. Quasi-Poisson regression was used to model the relationship between CHS and drug spending.

b For binary, ordinal, and multinomial logistic regression models, adjusted odds ratios (95% CI) were reported for a 1000-unit increase in CHS, adjusting for age and sex. For linear regression models, adjusted effect coefficients (95% CI) for a 1000-unit increase in CHS, adjusting for age and sex. For quasi-Poisson regression models, the adjusted risk ratios (95% CI) were reported for a 1000-unit increase in CHS, adjusting for age and sex.