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. 2013 Nov 6;8(11):e79724. doi: 10.1371/journal.pone.0079724

Table 1. Parameters of high-fat diet-induced obese mice.

HFD + Mifepristone (mg/kg BW/day) 0 0.1 1 30
Total body weight [g] 45.2 ± 1.1 43.8 ± 1.4 44.6 ± 1.1 44.0 ± 1.4
Food consumption [g/day] 3.04 ± 0.04 2.96 ± 0.06 3.04 ± 0.05 3.04 ± 0.04
Fasting blood glucose [mg/dL] 234.3 ± 9.4 190.2 ± 8.7 * 177.7 ± 13.9 ** 179.8 ± 14.6 **

Seven-week-old C57BL/6NCr Slc mice received a high-fat diet (HFD) and were orally treated with either mifepristone (0.1, 1 or 30 mg/kg bw/day) or vehicle (HFD alone) for 22 consecutive weeks (n = 8 in each group). At the 28 weeks of age, animals were subjected to a fasting blood glucose test. * p < 0.05, ** p < 0.01 versus HFD fed mice that did not receive mifepristone.