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. 2013 Nov 6;8(11):e80043. doi: 10.1371/journal.pone.0080043

Figure 5. Crystal structures of Plk1 PBD in complex with PL-74.

Figure 5

The overlay of the crystal structures of the Plk1 PBD-bound PL-74 (white) over the previously reported unligated Plk1 PBD (cyan) revealed that the N-terminal cyclohexyl moiety of PL-74 bound deeply into the Tyr-rich hydrophobic channel.