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. 2013 Nov 6;8(11):e80089. doi: 10.1371/journal.pone.0080089

Figure 2. Bone marrow MCPIP1 deficiency caused hematological disturbance.

Figure 2

A. Giemsa stained blood smears showed MCPIP1−/− bone marrow cell recipients contain dramatically reduced number of red blood cells. B. Vetscan HMT blood cell analysis showed reduced blood red cell (RBC) number, hemoglobin (HGB) concentration and hematocrit (HCT), as well as increased red cell distribution width (RDWc) which is calculated as Standard deviation ÷ mean cell volume x 100. C. Blood leukocyte profile showed increased number of neutrophils in MCPIP1−/− bone marrow cell recipients. D. Platelet related parameters of mice obtained by Vetscan HMT analysis. Parameters include total blood platelet count, platelet hematocrit (PCT), mean platelet volume (MVP), and platelet distribution width (PDWc) which is calculated using equation RDWc(%)  =  (Standard deviation ÷ mean cell volume) x 100. N = 6 (WT) or 9 (MCPIP1−/−).