TABLE 2.
Plasma and saliva measures
| Hypertension | ||||
| All | No | Yes | P | |
| Plasma measures | ||||
| Cholesterol (g/l) | 2.2 (1.5–2.8) | 2.2 (1.7–2.8) | 2.2 (1.4–2.8) | 0.45 |
| HDL cholesterol (g/l) | 0.49 (0.30–0.76) | 0.52 (0.35–0.77) | 0.47 (0.28–0.75) | 0.006 |
| Tryglycerides (g/l) | 0.96 (0.57–2.10) | 0.90 (0.57–1.70) | 1.08 (0.56–2.19) | 0.0003 |
| Glucose (g/l) | 0.99 (0.87–1.21) | 0.97 (0.86–1.20) | 1.01 (0.87–1.21) | 0.009 |
| Creatinine (mg/l) | 10.0 (8.0–14.0) | 10.0 (8.0–13.0) | 10.0 (8.0–15.0) | 0.23 |
| CRP (μg/ml) | 1.05 (0.17–8.18) | 0.76 (0.22–5.65) | 1.41 (0.17–12.14) | 0.0002 |
| Saliva measures | ||||
| Volume (ml) | 3.0 (1.3–5.5) | 3.2 (1.5–5.2) | 2.8 (1.2–5.5) | 0.07 |
| Lysozyme (μg/ml) | 5.0 (2.1–37.9) | 4.1 (2.1–22.8) | 5.6 (2.1–47.7) | 0.008 |
| MMP-9 (pg/ml) | 202.2 (9.3–1105.9) | 147 (4–1116) | 263 (15–1081) | 0.002 |
| LTB4 (pg/ml) | 300 (58–2401) | 299 (43–1357) | 304 (78–2629) | 0.09 |
| PGE2 (pg/ml) | 118.5 (28.0–506.4) | 101 (25–492) | 127 (32–511) | 0.047 |
| Creatinine (mg/l) | 0.24 (0.05–0.72) | 0.23 (0.05–0.57) | 0.26 (0.06–0.90) | 0.14 |
| CRP (ng/ml) | 0.21 (0.0002–5.20) | 0.16 (0.0002–1.56) | 0.30 (0.0002–6.21) | 0.002 |
Values are expressed as median and 5–95% confidence interval. Statistical analyses were performed using Mann–Whitney U-test. CRP, C-reactive protein; HDL, high-density lipoprotein; LDL, low-density lipoprotein; LTB4, leukotriene B4; MMP-9, matrix metalloproteinase 9; PGE2, prostaglandin E2.