Figure 4. Surgical stress delays prostate involution induced by androgen ablation.

C575BL/6J mice received subcutaneous injections of bicalutamide (50 mg/kg, once daily) and MDV3100 (10 mg/kg, once daily) with or without sham castration. ICI118,551 (ICI) was given 30 minutes before sham castration. 2 days later prostates were excised, dissected, and weighted. At least 3 mice were used for each data point. Error bars represent SD from the average.