Table 1. Fetal arterial blood gases, pH, hematocrit, blood lactate, and arterial pressure and heart rate before (−1 h), at the end of (+10 mins), and 1 to 48 h after occlusion of the umbilical cord at 132 days gestation.
Time relative toonset of UCO | −1 h | +10 mins | +1 h | +2 h | +4 h | +8 h | +12 h | +24 h (n = 4) | +48 h (n = 4) |
p O2 (mmHg) | 20.2±0.7 | 4.9±1.6* | 21.2±0.6 | 20.4±0.5 | 18.6±1.5 | 19.3±1.0 | 18.2±1.1 | 19.4±1.3 | 21.0±1.0 |
p CO2 (mmHg) | 55.4±1.0 | 126.2±14.1* | 53.5±0.9 | 51.4±1.0* | 52.2±1.2* | 54.1±1.1 | 53.8±0.6 | 54.0±1.2 | 53.3±1.4 |
O2 saturation (%) | 48.5±3.2 | 5.0±2.4* | 47.6±2.7 | 48.3±2.3 | 44.1±5.5 | 44.1±4.8 | 41.2±4.5 | 46.1±4.4 | 48.9±4.0 |
pH | 7.35±0.01 | 6.95±0.07* | 7.28±0.02* | 7.33±0.01 | 7.35±0.01 | 7.35±0.01 | 7.35±0.01 | 7.35±0.00 | 7.34±0.01 |
Blood lactate (mmol/L) | 1.6±0.2 | 8.9±1.6* | 6.6±1.2* | 4.6±0.8* | 3.5±0.7* | 3.3±0.8 | 2.8±0.7 | 1.7±0.2 | 1.7±0.3 |
Base Excess (mmol/L) | 3.3±0.4 | −10.0±2.5* | −2.7±1.0* | 0.1±0.7* | 1.9±0.4* | 3.0±0.4 | 3.0±0.4 | 2.8±0.4 | 2.3±0.6 |
Hematocrit | 32.2±0.9 | 34.7±0.8* | 31.5±1.3 | 30.7±1.1* | 30.6±1.2* | 30.3±1.0* | 30.5±1.0 | 31.0±0.6 | 31.5±0.3 |
Arterial pressure (mmHg) | 43.1±2.6 | 47.6±1.8 | 48.1±2.9 | 47.0±2.7* | 41.7±0.9 | 41.2±0.7 | 42.1±0.7 | n/a | n/a |
Heart rate (beats/min) | 157.1±3.1 | 212.7±39.6 | 185.0±7.7* | 157.0±5.9 | 155.9±3.1 | 154.2±3.8 | 157.0±4.5 | n/a | n/a |
Data shown as mean ± SEM, n = 5 throughout, except for +24 h and +48 h (n = 4).
p<0.05, compared to values at −1 h. (n/a = data not available).