Table 1. Description of patients with Parkinson’s disease.
patient | Age [years] | DD [years] | levodopa [mg] | UPDRS III | H-Y | DBS target | task | neurons |
1 | 64 | 14 | 1375 | 31 | 2.0 | STN | SEM | 12 |
2 | 61 | 14 | 1200 | 37 | 2.5 | STN | SEM | 7 |
3 | 46 | 15 | 1000 | 40 | 3.0 | STN | SEM | 15 |
4 | 63 | 30 | 1250 | 50 | 3.0 | STN | SEM | 3 |
5 | 53 | 12 | 700 | 37 | 2.5 | STN | SEM | 14 |
6 | 69 | 9 | 750 | 47 | 3.0 | STN | SEM | 5 |
7 | 49 | 12 | 1550 | 65 | 4.0 | STN | SEM | 7 |
8 | 59 | 12 | 600 | 30 | 2.5 | STN | SEM | 8 |
9 | 63 | 14 | 1350 | 21 | 2.0 | GPi | SEM | 4 |
10 | 53 | 10 | 750 | 42 | 4.0 | GPi | SEM | 11 |
11 | 53 | 11 | 1663 | 45 | 2.5 | STN | SEM | 5 |
12 | 57 | 26 | 2000 | 59 | 4.0 | STN | SEM | 12 |
13 | 28 | 3 | 720 | 10 | 2.0 | GPi | SEM | 6 |
14 | 64 | 17 | 1500 | 31 | 2.5 | STN | SEM | 12 |
15 | 53 | 12 | 1000 | 40 | 4.0 | STN | SEM | 9 |
16 | 44 | 10 | 1130 | 23 | 2.0 | GPi | SEM, VGS | 2 |
17 | 42 | 9 | 740 | 33 | 3.0 | STN | SEM, VGS | 20 |
18 | 55 | 19 | 1980 | 35 | 2.0 | STN | SEM, VGS | 16 |
19 | 60 | 14 | 1060 | 18 | 2.0 | STN | SEM, VGS | 15 |
Age – age on the day of surgery; STN – subthalamic nucleus; GPi – globus pallidus interna; DD – Parkinsońs disease duration; Levodopa – dose/day in mg including levodopa equivalent dosage of dopamine agonist; patient 4 was also treated with mianserin; patients 6, 7, 8, 9, 10 with citalopram and 16 with bupropion; UPDRS III – motor score of the Unified Parkinsońs Disease Rating Scale in OFF medication condition; H-Y – Hoehn and Yahr stage in OFF medication condition; DBS target – nucleus chosen for bilateral deep brain stimulation; SEM – scanning eye movement task; VGS – visually guided saccade task; neurons – number of neurons identified in the basal ganglia.