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. Author manuscript; available in PMC: 2014 Jul 11.
Published in final edited form as: J Med Chem. 2013 Jun 25;56(13):10.1021/jm400575x. doi: 10.1021/jm400575x

Scheme 2.

Scheme 2

Conversion of 3-Nitro and 3,5-Dinitro N-Aryl-2-arylethenesulfonamides to corresponding Amines (6) a

aReagents and conditions: (a) Sodium hydrosulfite, acetone / water (2:1), 50 °C, 30 min, 40%; (b) Iron powder, MeOH / AcOH (2:1), 80 °C, 2 h, 55%.