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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Aging Cell. 2013 Jul 29;12(6):10.1111/acel.12127. doi: 10.1111/acel.12127

Fig. 5. Effect of lipoic acid on PGC1α transcriptional pathway and mitochondrial biogenesis.

Fig. 5

Equal amount of homogenate samples from brain cortices of Fischer 344 rats were loaded on the gel. Percentages (relative to 6-month old rats) of (A) p-AMPK-Thr172; (B) Sirt1; (C) PGC1α; (D) PGC1α acetylation levels; (E) NRF1. (F) Mitochondrial biogenesis was assessed by the ratio of COX3/18SrDNA, determined by real-time PCR. *p < 0.05, n ≥ 6.