Table 2. Patient and treatment factors associated with being at goal medication dose at 12-month follow-up.
Beta-Blocker | Statin | ACE/ARB | ||||
---|---|---|---|---|---|---|
OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | |
Medication dose at discharge | ||||||
Low dose | 0.50 (0.30-0.83) | 0.008 | 0.67 (0.47-0.95) | 0.024 | 0.86 (0.34-2.15) | 0.748 |
Moderate dose | 0.93 (0.55-1.59) | 0.799 | 1.36 (1.01-1.82) | 0.043 | 1.83 (0.78-4.27) | 0.162 |
Goal dose | 6.08 (3.70-10.01) | <0.001 | 8.22 (6.20-10.90) | <0.001 | 5.80 (2.56-13.16) | <0.001 |
| ||||||
Age (per 1 y) | 0.98 (0.97-1.00) | 0.047 | 1.00 (0.98-1.02) | 0.880 | 1.00 (0.97-1.03) | 0.934 |
Female sex | 0.94 (0.72-1.23) | 0.638 | 1.01 (0.86-1.19) | 0.872 | 0.75 (0.43-1.29) | 0.296 |
White race | 1.25 (0.93-1.68) | 0.145 | 1.02 (0.85-1.24) | 0.809 | 1.04 (0.61-1.79) | 0.880 |
Hypertension | 1.46 (1.07-2.00) | 0.017 | 1.02 (0.87-1.20) | 0.830 | 1.33 (0.75-2.34) | 0.327 |
Depression | 0.98 (0.71-1.36) | 0.910 | 1.02 (0.84-1.24) | 0.807 | 0.67 (0.35-1.30) | 0.235 |
Diabetes mellitus | 1.40 (1.08-1.82) | 0.011 | 0.86 (0.72-1.02) | 0.083 | 0.97 (0.59-1.61) | 0.906 |
Chronic lung disease | 1.26 (0.83-1.90) | 0.277 | 0.89 (0.66-1.19) | 0.433 | 1.33 (0.64-2.76) | 0.443 |
ST-elevation MI | 1.04 (0.80-1.36) | 0.752 | 1.06 (0.91-1.24) | 0.429 | 0.83 (0.50-1.38) | 0.465 |
GRACE score (per 1 pt) | 1.00 (1.00-1.01) | 0.365 | 1.00 (1.00-1.01) | 0.407 | 1.00 (0.98-1.01) | 0.724 |
Follow-up rate (per 1 visit per month) |
1.09 (0.82-1.45) | 0.560 | 1.01 (0.85-1.21) | 0.875 | 1.33 (0.87-2.03) | 0.184 |
Left Ventricular Dysfunction | 1.88 (1.40-2.53) | <0.001 | NA | NA | ||
SBP* (per 1 mmHg) | 1.00 (0.99-1.01) | 0.727 | NA | 1.01 (1.00-1.03) | 0.092 | |
Heart rate* (per 1 bpm) | 1.00 (0.99-1.01) | 0.426 | NA | NA | ||
GFR* (per 1 mL/min/1.73m2) | NA | NA | 1.00 (0.99-1.01) | 0.627 |
ACE/ARB, angiotensin converting enzyme inhibitor/angiotensin II receptor blocker; MI, myocardial infarction; GRACE, Global Registry of Acute Coronary Events; GFR, glomerular filtration rate
Assessed at hospital discharge