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. Author manuscript; available in PMC: 2014 Nov 5.
Published in final edited form as: J Am Coll Cardiol. 2013 Aug 21;62(19):10.1016/j.jacc.2013.04.102. doi: 10.1016/j.jacc.2013.04.102

Table 2. Patient and treatment factors associated with being at goal medication dose at 12-month follow-up.

Beta-Blocker Statin ACE/ARB
OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value
Medication dose at discharge
 Low dose 0.50 (0.30-0.83) 0.008 0.67 (0.47-0.95) 0.024 0.86 (0.34-2.15) 0.748
 Moderate dose 0.93 (0.55-1.59) 0.799 1.36 (1.01-1.82) 0.043 1.83 (0.78-4.27) 0.162
 Goal dose 6.08 (3.70-10.01) <0.001 8.22 (6.20-10.90) <0.001 5.80 (2.56-13.16) <0.001

Age (per 1 y) 0.98 (0.97-1.00) 0.047 1.00 (0.98-1.02) 0.880 1.00 (0.97-1.03) 0.934
Female sex 0.94 (0.72-1.23) 0.638 1.01 (0.86-1.19) 0.872 0.75 (0.43-1.29) 0.296
White race 1.25 (0.93-1.68) 0.145 1.02 (0.85-1.24) 0.809 1.04 (0.61-1.79) 0.880
Hypertension 1.46 (1.07-2.00) 0.017 1.02 (0.87-1.20) 0.830 1.33 (0.75-2.34) 0.327
Depression 0.98 (0.71-1.36) 0.910 1.02 (0.84-1.24) 0.807 0.67 (0.35-1.30) 0.235
Diabetes mellitus 1.40 (1.08-1.82) 0.011 0.86 (0.72-1.02) 0.083 0.97 (0.59-1.61) 0.906
Chronic lung disease 1.26 (0.83-1.90) 0.277 0.89 (0.66-1.19) 0.433 1.33 (0.64-2.76) 0.443
ST-elevation MI 1.04 (0.80-1.36) 0.752 1.06 (0.91-1.24) 0.429 0.83 (0.50-1.38) 0.465
GRACE score (per 1 pt) 1.00 (1.00-1.01) 0.365 1.00 (1.00-1.01) 0.407 1.00 (0.98-1.01) 0.724
Follow-up rate (per 1 visit per
month)
1.09 (0.82-1.45) 0.560 1.01 (0.85-1.21) 0.875 1.33 (0.87-2.03) 0.184
Left Ventricular Dysfunction 1.88 (1.40-2.53) <0.001 NA NA
SBP* (per 1 mmHg) 1.00 (0.99-1.01) 0.727 NA 1.01 (1.00-1.03) 0.092
Heart rate* (per 1 bpm) 1.00 (0.99-1.01) 0.426 NA NA
GFR* (per 1 mL/min/1.73m2) NA NA 1.00 (0.99-1.01) 0.627

ACE/ARB, angiotensin converting enzyme inhibitor/angiotensin II receptor blocker; MI, myocardial infarction; GRACE, Global Registry of Acute Coronary Events; GFR, glomerular filtration rate

*

Assessed at hospital discharge