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. 2013 Nov 7;4:138. doi: 10.3389/fphar.2013.00138

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Copyright © 2013 Gauthier, Ozvegy-Laczka, Szakacs, Sarkadi and Di Pietro.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of other modulators on ABGC2-specific intracellular glutathione depletion. Screening of Xanthones (Genoux-Bastide et al., 2011), Chalcones (Valdameri et al., 2012), and 6-Prenylchrysin (Ahmed-Belkacem et al., 2005) reveal a significant ABCG2-dependent intracellular glutathione depletion in 6-h incubation for some compounds, as indicated. The values represent means ± SD corresponding to at least two independent experiments performed in triplicates. t-test analysis: *p < 0.05, **p < 0.01.