Table 1.
Characteristic | Group 1 (n = 60) | miR-196b high (n = 28) | miR-196b low (n = 29) | P value | HOXA10 high (n = 29) | HOXA10 low (n = 28) | P value |
Age, yr | |||||||
Median (range) | 63 (32-83) | 66 (34-78) | 58 (32-83) | 0.134 | 64 (34-83) | 60 (32-78) | 0.134 |
> 65 | 15 (52) | 9 (32) | 15 (52) | 9 (32) | |||
Sex | |||||||
Male | 41 (68) | 19 (68) | 20 (69) | 0.928 | 18 (62) | 21 (75) | 0.294 |
Histologic type | |||||||
Diffuse | 27 (45) | 9 | 17 | 0.066 | 8 | 18 | 0.007 |
Intestinal | 23 (38) | 14 | 9 | 16 | 7 | ||
Mixed | 10 (17) | 5 | 3 | 5 | 3 | ||
T stage | |||||||
T1/T2 | 26 (43) | 10 (36) | 14 (48) | 0.337 | 11 (38) | 13 (46) | 0.516 |
T3/T4 | 34 (57) | 18 (64) | 15 (52) | 18 (62) | 15 (54) | ||
N stage | |||||||
N0/N1 | 36 (60) | 15 (54) | 19 (66) | 0.358 | 16 (55) | 18 (64) | 0.483 |
N2/N3 | 24 (40) | 13 (46) | 10 (34) | 13 (45) | 10 (36) | ||
AJCC stage1 | |||||||
I/II | 23 (38) | 11 (39) | 12 (41) | 0.872 | 11 (38) | 12 (43) | 0.705 |
III/IV | 37 (62) | 17 (61) | 17 (59) | 18 (62) | 16 (57) |
Based on the American Joint Committee on Cancer staging manual 6th edition. HOXA10: Homeobox A10; AJCC: American Joint Committee on Cancer.