Table 2.
Expression levels of epidermis genes and DNA methylation factors
| Gene group | Gene | Expression (young) | Expression (old) | q value |
|---|---|---|---|---|
| Epidermis keratins |
KRT1 |
14719.2 |
14954.2 |
1.0 |
| |
KRT2 |
7291.7 |
6154.7 |
1.0 |
| |
KRT5 |
5860.6 |
5247.7 |
1.0 |
| |
KRT10 |
26232.1 |
23374.7 |
1.0 |
| |
KRT14 |
5665.0 |
4430.4 |
1.0 |
| |
KRT15 |
382.1 |
400.1 |
1.0 |
| Epidermis structural factors |
LOR |
613.4 |
427.3 |
1.0 |
| |
FLG |
558.1 |
501.3 |
1.0 |
| |
FLG2 |
322.5 |
336.5 |
1.0 |
| Fibroblast markers (dermis) |
VIM |
41.0 |
54.0 |
1.0 |
| |
DES |
<0.1 |
<0.1 |
1.0 |
| DNA methylation factors |
DNMT1 |
9.5 |
7.3 |
1.0 |
| |
DNMT3A |
1.5 |
1.2 |
1.0 |
| |
DNMT3B |
1.4 |
1.5 |
1.0 |
| |
DNMT3L |
<0.1 |
<0.1 |
1.0 |
| |
UHRF1 |
1.3 |
1.2 |
1.0 |
| |
TET1 |
0.1 |
0.1 |
1.0 |
| |
TET2 |
8.4 |
6.9 |
1.0 |
| TET3 | 18.8 | 14 | 1.0 |