Table 1.
Description of UMs
| UM | Related to subsystem | No. reactions | No. metabolites | RNP | RNC |
|---|---|---|---|---|---|
| 1 |
Menaquinol Biosynthesis |
23 |
21 |
Mev, 2ombzl |
2ommbl |
| 2 |
Nucleotide Salvage Pathway |
22 |
15 |
- |
Hxan, xan, r1p, 2dr1p, thym, ura |
| 3 |
Pyridoxal 5-phosphate Biosynthesis |
7 |
6 |
- |
4hthr |
| 4 |
Lipopolysaccharide Biosynthesis |
4 |
4 |
- |
u3hga |
| 5 |
Siroheme Biosynthesis |
4 |
4 |
- |
uppg3 |
| 6 |
Arginine and Proline Metabolism |
2 |
2 |
- |
1pyr5c |
| 7 |
Transport, Extracellular (Fe2+) |
2 |
2 |
- |
Fe2+ |
| 8 |
Transport, Extracellular (K+) |
2 |
2 |
- |
K+ |
| 9 |
Superoxide Dismutase |
1 |
1 |
O2– |
- |
| 10 |
Acyl-Carrier Protein Synthase |
1 |
1 |
apoACP |
- |
| Total | 68 | 58 | 8 | 4 |
UM identified in B. cuenoti iCG238 GSM. Metabolite abbreviations: Mev (mevalonate), 2ombzl (2-Octaprenyl-6-methoxy-1,4-benzoquinol), 2ommbl (2-Octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol), hxan (Hypoxanthine), xan (Xanthine), r1p (Ribose-1-phosphate), 2dr1p (2-deoxy-D-Ribose-1-phosphate, thym (Thymine), ura (Uracil) 1pyr5c (1-Pyrroline-5-carboxylate), 4hthr (4-Hydroxy-L-threonine), u3hga (UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine), uppg3 (Uroporphyrinogen), apoACP (apoprotein [acyl carrier protein]). The relation between an UM and a subsystem was established according to the most frequent subsystem associated to the reactions of the UM.