Table 1.
Inclusion criteria: |
|
1. |
Stable coronary heart disease with CCS functional classification of angina class I to III |
2. |
Low self-rated physical activity |
3. |
Condition after percutaneous coronary intervention > 4 weeks until < 26 weeks or > 52 weeks after index percutaneous coronary intervention |
4. |
Residence < 50 km radius of the study center (city of Mainz) |
5. |
If treatment with beta blockers or ivabradine then stable > 4 weeks |
Exclusion criteria: |
|
1. |
Acute coronary syndrome or myocardial infarction < 8 weeks |
2. |
Coronary stenosis of the dominant vessel > 25% or high grade stenosis of the left coronary artery |
3. |
Heart failure with left ventricular ejection fraction < 40% |
4. |
NYHA III to IV |
5. |
Severe heart valve disorder |
6. |
Insulin dependent diabetes |
7. |
Orthopedic or other disorders, which preclude regular physical activity |
8. |
Coronary artery bypass surgery < 6 months before index PCI |
9. |
Severe obesity (BMI ≥ 40) |
10. |
Need for systemic immunosuppression with cortisone or methotrexate |
11. |
Kidney failure with need for dialysis |
12. | Intake of nitrates < 12 hours |
CCS severity of angina according to the Canadian Cardiovascular Society, NYHA symptoms of heart failure according to the New York Heart Association, PCI percutaneous coronary intervention.