Table 2.
Lipase inhibitory activity of Polygonum cuspidatum fractions
| Scientific name | Fraction | Conc. (μg/ml) | Inhibition (%) a | IC 50 (μg/ml) |
|---|---|---|---|---|
|
Polygonum cuspidatum |
Ethanol extract (POCU1) |
0 |
0 ± 4.8 |
72.5 ± 6.7 |
| 50 |
45.8 ± 1.9 |
|||
| 100 |
54.9 ± 0.3 |
|||
| |
|
150 |
62.7 ± 3.2 |
|
| |
n-Hexane (POCU1h) |
0 |
0 ± 4.8 |
326.9 ± 36.6 |
| 200 |
33.9 ± 3.2 |
|||
| 300 |
44.7 ± 7.3 |
|||
| |
400 |
64.1 ± 7.2 |
||
| |
Ethyl acetate (POCU1ea) |
0 |
0 ± 4.8 |
26.4 ± 1.9 |
| 20 |
44.6 ± 3.4 |
|||
| 30 |
52.5 ± 0.7 |
|||
| |
40 |
54.1 ± 0.4 |
||
| |
n-Butanol (POCU1b) |
0 |
0 ± 4.8 |
15.8 ± 2.6 |
| 10 |
46.5 ± 0.3 |
|||
| 15 |
49.7 ± 2.4 |
|||
| |
20 |
52.8 ± 1.4 |
||
| Water (POCU1w) |
0 |
0 ± 4.8 |
295.8 ± 10.9 | |
| 200 |
46.6 ± 1.6 |
|||
| 300 |
50.1 ± 0.2 |
|||
| 400 | 52.8 ± 0.6 |
a Results are the mean ± S.E.M. (n = 3).