Table 4.
Comparison of CNAs by a-CGH in recurrent regions in primary tumors and metastases
|
Recurrent region |
Detected in [number of cases / informative (%)] |
||
|---|---|---|---|
| Primary tumors | Metastases | All tumors | |
|
No of samples |
n = 18 |
n = 12 |
n = 30 |
|
Losses |
|
|
|
| 9pter-p13.2 |
2 / 18 (11%) |
1 / 12 (8%) |
3 / 30 (10%) |
| 9p13.1-11.2 |
3 / 18 (17%) |
2 / 12 (17%) |
5 / 30 17%) |
| 11q23.1-qter |
4 / 18 (22%) |
3 / 12 (25%) |
7 / 30 (23%) |
| 13q14.11-21.32 |
2 / 18 (11%) |
1 / 12 (8%) |
3 / 30 (10%) |
| 13q33.1 |
2 / 18 (11%) |
1 / 12 (8%) |
3 / 30 (10%) |
| 16q12.2-qter |
1 / 18 (6%) |
4 / 12 (33%) |
5 / 30 (17%) |
| 18pter-11.21 |
12 / 18 (67%) |
8 / 12 (67%) |
20 / 30 (67%) |
| 18q12.1-21.31 |
10 / 18 (56%) |
8 / 12 (67%) |
18 / 30 (60%) |
|
Gains |
|
|
|
| 4pter-qter |
4 / 18 (22%) |
4 / 12 (%) |
8 / 30 (27%) |
| 5pter-qter |
4 / 18 (22%) |
3 / 12 (25%) |
7 / 30 (23%) |
| 7p22.3 |
1 / 18 (6%) |
2 / 12 (17%) |
3 / 30 (10%) |
| 7p22.2-22.1 |
1 / 18 (6%) |
2 / 12 (17%) |
3 / 30 (10%) |
| 7q22.1 |
1 / 18 (6%) |
2 / 12 (17%) |
3 / 30 (10%) |
| 7q22.3-qter |
1 / 18 (6%) |
3 / 12 (25%) |
4 / 30 (13%) |
| 14q11.2 |
4 / 18 (22%) |
5 / 12 (42%) |
9 / 30 (30%) |
| 14q32.2-32.31 |
3 / 18 (17%) |
3 / 12 (25%) |
6 / 30 (20%) |
| 20pter-p11.21 |
4 / 18 (22%) |
4 / 12 (33%) |
8 / 30 (27%) |
| 20q11.1-11.21 |
5 / 18 (28%) |
2 / 12 (17%) |
7 / 30 (23%) |
| 20q12-qter | 6 / 18 (33%) | 5 / 12 (42%) | 11 / 30 (37%) |