Table 12.

Enriched¹ functional annotation clusters and most enriched Gene Ontology and KEGG categories by SNP association

SNP association	Cluster score	Category	Name	Number of genes	P-value
General	11.39	Molecular Function FAT	nucleotide binding	54	1.4E-19
	3.6	Biological Process FAT	protein amino acid phosphorylation	16	3.4E-05
		KEGG Pathway	MAPK signaling pathway	11	2.1E-04
		Molecular Function FAT	protein serine/threonine kinase activity	12	4.1E-04
	3.02	Molecular Function FAT	substrate specific channel activity	18	4.0E-09
		Biological Process FAT	ion transport	17	6.5E-06
Breed-dependent	16.11	Molecular Function FAT	nucleotide binding	76	3.5E-26
		Biological Process FAT	protein amino acid phosphorylation	27	7.8E-11
	9.83	Biological Process FAT	phosphorus metabolic process	35	7.2E-13
		Molecular Function FAT	protein kinase activity	25	2.3E-09
	5.42	Biological Process FAT	ion transport	32	2.3E-13
		Molecular Function FAT	ion channel activity	21	5.4E-10
	4.35	Biological Process FAT	membrane invagination	9	7.4E-06
Diet-dependent	16.71	Molecular Function FAT	nucleotide binding	65	2.1E-26
		Biological Process FAT	phosphorus metabolic process	33	5.0E-15
	3.23	Molecular Function FAT	metallopeptidase activity	12	1.5E-07
		Biological Process FAT	proteolysis	14	7.0E-03

¹Cluster enrichment score > 3. The most significant Gene Ontology molecular function, biological process and KEGG pathway categories within each cluster are listed.