Table 1.
Devices designed to remove endotoxin and cytokines in patients with septic shock.
| Device | Company | Composition | Mechanism | Substance eliminated |
|---|---|---|---|---|
| Toraymyxin 20R | Toray Industries, Japan | Polymyxin B covalently bound to polypropylene-polystyrene fibers fabric | Adsorption | Endotoxin |
|
| ||||
| LPS adsorber | Alteco Medical, Sweden | Synthetic polypeptide bound to porous polyethylene discs | Adsorption | Endotoxin |
|
| ||||
| oXiris | Gambro-Hospal, France | AN69-based membrane, surface treated with a polyethyleneimine (PEI) and grafted with heparin | Adsorption Convection |
Endotoxin Cytokines |
|
| ||||
| MATISSE | Fresenius SE, Germany | Human serum albumin immobilised on polymethacrylate beads | Adsorption | Endotoxin |
|
| ||||
| CPFA | Bellco, Italy | Polyethersulfone Plasma filter with adsorption on an unselective hydrophobicresin cartridge, and a synthetic high-permeability polyethersulfone hemofilter for continuous hemofiltration | Adsorption Plasma filtration |
Cytokines |
|
| ||||
| Cytosorb | Cytosorbents, USA | Polystyrenedivinyl benzene copolymer beads with a biocompatible polyvinylpyrrolidone coating. | Adsorption Convection |
Cytokines |